Buy Melanotan 2 Research Peptide – A Peptide of Great Interest In Modern Science
The alpha-melanocyte stimulating hormone is a vital component in a biological system. It is vital for inducing melanogenesis or skin tanning process. Melanotan 2 is a synthetic, injectable of the naturally-occurring alpha-melanocyte stimulating hormone. The variant of the endogenous hormone has undergone modifications to improve its efficacy and functionality. Melanotan 2 is supplied for research purposes and has gained huge popularity among researchers and scientists. The melanotan 2 peptide up-regulates conversion of eumelanin to melanin in the epidermal layer of the skin. Uncontrolled multiplication of epidermal cells is known to induce skin cancer or melanoma. Biologically-synthesized melanotan 2 peptide is categorized as the second generation of natural alpha-melanocyte stimulating hormone. Melanotan 2 was produced after the discovery of melanotan 1 by researchers in the University of Arizona. Melanogenesis is a crucial process and without it, cells of the skin would multiply indefinitely. The forming of skin pigmentation process is a biological process that prevents damage from harmful ultraviolet B rays of the sun.
Unprecedented cellular multiplication can cause a wide array of problems on the skin. Melanoma and actinic keratosis are two conditions characterized by irregular multiplication of epidermal layer of the skin. Melanotan 2 is a biologically-synthesized peptide vital for accentuating the release of melanin or conversion of eumelanin to melanin in the epidermal layers of the skin. Melanotan 2 accentuates the production of melanin on the skin and utilizes G-coupled protein receptors. The G-coupled protein activates melanocortin receptors to begin conversion of eumelanin to melanin. Moreover, recent research studies showed that activation of melanocortin receptors up-regulates metabolism, libido and appetite of the test subject. Recent studies done on mice showed that melanotan 2 works via a complex signaling pathway that has other net positive effects on the test subjects. Other benefits of the melanotan 2 peptide include appetite suppression, tanning of the skin and preventing deposition of fat cells in peripheral and visceral organs.
Melanotan 2 is able to induce skin tanning without exposure to sunlight. This is an area of study that has gained huge interest among researchers. This is particularly important for preventing skin-related conditions and unusual cellular multiplication of cells in epidermal layers of the skin. A recent study showed that the melanotan 2 peptide has an up-regulation effect on libido and sexual arousal. When melanotan 2 is administered to research mice, they showed erection and solicited their female counterparts. Sexual characteristics showed by male mice were attributed to the administration of melanotan 2 because the control group did not show any of these features. On the other hand, female mice showed reddening of sexual organs and solicitation behavior. Studies are underway to determine the efficiency of the melanotan 2 peptide in inducing tanning without exposure to the sun.
Melanotan 2 Mechanism of Action
Melanotan 2 has a low molecular weight which is vital for traversing various cells and tissues to the target organ. Reduction of molecular weight and density are two features that make melanotan 2 a peptide of interest in modern science. Melanotan 2 is produced by cells in the epidermis in response to exposure to ultraviolet rays. The synthetic version of bremelanotide stimulating hormone mimics natural function of the endogenous alpha-melanocyte stimulating hormone. According to findings from research, melanotan 2 has aphrodisiac functions on test subjects. However, it is imperative to note that no synthetic peptide has been approved for human consumption. Studies showed that the melanotan 2 peptide can help reduce the effects of tumor genesis.
Recent studies showed that administration of the melanotan 2 peptide resulted in a reduction of insulin serum and cholesterol. However, it does not affect acetylcholine levels in a biological system. Acetylcholine is an important component because without it, signal transduction from one part of the body to another will not happen. Neuronal transfer of information varies from one species to another especially with changes in levels of acetylcholine levels. Axon potential on neurons is crucial in bringing about a net effect in information transfer. Carnitine and palmitoyl transferase are the only known inhibitors of acetylcholine. External administration of synthetic melanotan 2 peptide is essential in bringing about a net positive effect in the release of various hormones and components in the test subject. The alpha-melanocyte stimulating hormone is a nonselective agonist and it is vital to note that it works on MC1R, MC4R, MC3R and MC5R. Melanocortin receptors are important in changing signal transduction and information to specific cells.
Other alpha-melanocytes stimulating secretagogues are known to stimulate signal transduction by binding to all melanocortin receptors. Melanotan 2 is under research to determine its potency and efficacy in accentuating the melanogenesis process with higher efficiency and safety. Exposure to ultraviolet radiation causes changes in metabolic pathways and results in the conversion of eumelanin to melanin. There are complex systems in the system of test subjects which modification of various components results in net positive effects on the epidermal layer of the skin. The melanotan 2 peptide binds to the skin, causing adenylate cyclase production and activation of cyclic adenosine monophosphate.
Production of adenosine monophosphate is an important process because the phosphorylation process cannot occur when adenosine monophosphate is not produced. A phosphate group of adenosine monophosphate is activated and binds to the cyclic adenosine monophosphate response binding element (CREB). Moreover, phosphorylation of CREB results in cyclic adenosine monophosphate response element to microphthalmia transcription factor gene. When the binding occurs, it activates the conversion of eumelanin into melanin in the skin. The tanning process is a natural response of the body to prevent cells from exposure to harmful ultraviolet rays. Initial research showed that the melanotan 2 polypeptide is effective in alleviating various skin conditions including skin cancer.
Evolution of the Melanotan 2 Peptide in Research
Pilot studies of melanotan 2 showed that it has numerous potent melanotropin activities in vitro. According to research conducted on mice, a placebo was given to test subjects but the melanotan 2 peptide was not administered. It is imperative to note that administration of the melanotan 2 polypeptide should depend on the weight of the test subject. Subcutaneous injection is effective because it reduces chances of degradation by enzymes. The dosage varies in test subjects and you should first weigh them to determine the effective dosage. Test subjects injected with the melanotan 2 peptide showed mild nausea and site reactions. It is recommended that you change the administration site to avoid inflammation and injury. Yawning and stretching seemed to appear immediately after the melanotan 2 peptide was administered. However, reaction correlates with the dose administered and you should understand the working mechanism of melanotan 2 before injecting it into the test subject.
According to research, the melanotan 2 peptide has over 89% efficacy in accentuating sunless tanning than any other peptides in the market. It is imperative to note that for even tanning to occur, dosage administration should remain constant. Moreover, application of the melanotan 2 peptide should be done in a controlled setting. Currently, the melanotan 2 peptide supplied in the market dosage varies from 0.25 mg per kilogram to 2 mg per kilogram. The melanotan 2 peptide should be stored between 2 and 8 degree Celsius to prevent amino acid degradation or reduction in efficacy. The alpha-melanocyte stimulating hormone is an endogenously-produced hormone with a shorter half-life and its mechanism of action is through stimulation of melanocytes in the skin. The composition of alpha-melanocyte stimulating hormone is vital in creating a long-lasting peptide with higher efficacy and potency. Tissue exposure changes the orientation of the melanotan 2 peptide and you should monitor results every hour to avoid any changes in a biological system. Since synthetic melanotan 2 peptide is still under research, there could be unpredicted reaction on the test subject.
According to scientific study, the alpha-melanocyte stimulating hormone produced by the pituitary gland works on endocrine processes such as water retention, growth, development, pain and blood regulation. Alpha melanocyte stimulating hormone production can be increased by the administration of melanocyte stimulating peptides. Specifically, the melanotan 2 peptide works on melanocortin which are known to induce pigmentation. The half-life of a synthetic melanotan 2 hormone is enhanced to increase its bioavailability in a biological system. According to tests done in a scientific setting, melanotan 2 is very crucial in accentuating various biological processes that could otherwise affect the skin. Generation of new epidermal cells is important in combating the effects of cellular deterioration. These conditions present a new avenue for producing cells that could not have been produced if there is a low or failure of receptors to bind to the ligand.
Melanotan 2 and Skin Protection
The primary focus of the melanotan 2 peptide is on its ability to induce sunless tanning. Tanning is an important process that occurs in a biological system because uneven multiplication of epidermal cells would occur if it is not monitored. The rate of melanocortin conversion varies from one species to another species. However, it is imperative to note that scientific studies can stimulate the production of melanin without exposure to sun rays. This is effective in reducing the effects of ultraviolet radiation that could otherwise cause certain types of cancer. Scientific research showed that melanogenesis is not caused by exposure of skin cells to ultraviolet rays. It is the changes in deoxyribonucleic acid that are major causes of uneven cellular multiplication. DNA damage is a dangerous process because it affects molecular level and could lead to adverse side effects if not curtailed. Moreover, the melanotan 2 peptide is known to reduce fats deposition in visceral and peripheral organs.
Potential Side Effects of Melanotan 2
While the melanotan 2 peptide has been touted as the most effective melanocortin-inducing peptide, there are potential side effects associated with it. Negative side effects of melanotan 2 include hyperpigmentation or new moles, nausea, appetite suppression, dizziness, face flushing and lightheadedness, among others.
According to scientific studies, the spontaneous effects on libido associated with melanotan 2 are in relation to various scientific findings which suggest that the peptide is linked to hormonal stimulation related to libido. According to scientific studies, these side effects begin to wane during the course of study. It is imperative to note that the full effects and overall functionality of the melanotan 2 peptide are still under scientific study and human consumption of the peptide is not allowed. The use and effects of melanotan 2 should be confined to controlled areas like laboratories or research centers. It is important to note that any changes in the scientific area of study could cause an adverse effect on test subjects. The melanotan 2 peptide should be stored between 2 and 8 degree Celsius to prevent amino acid degradation or reduction in efficacy.
Where to Buy MelanotanMelanotide Peptide 2
Since melanotan 2 peptide has not been approved for human consumption. However, it is imperative that you buy peptides from trusted vendors to avoid inconclusive research or adverse side effects of melanotan 2. In most cases, these products contain other ingredients such as mannitol and it is synthetically manufactured to mimic the natural production of the alpha-melanocyte hormone. Purchasing a product from a reputable vendor saves you a great deal of trouble because findings from research studies can be used as a benchmark for further investigation. To eliminate the risks of buying counterfeit products, it is imperative that you choose specific companies that supply melanotan 2 peptides. Usually, melanotan 2 peptides have undergone sterilization to prevent transfer of microbes to test subjects. Moreover, there is no alteration of amino acids on polypeptide sequence to enhance its activity. Moreover, buying the melanotan 2 peptide from a trusted vendor is vital because with the use of a reliable synthetic peptide, results of a certain degree of accuracy in a laboratory setting can be obtained.